Essie99
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the general rule of thumb is that the _____a substance's atoms and the _____ the bonds, the harder the substance

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MissPhiladelphia
The general rule of thumb is that the smaller a substance's atoms and the stronger the bonds, the harder the substance to react and interact with other atoms. Since the stability is higher. Hope this answers the question. Have a nice day.

Answer:

Smaller and stronger.

Step-by-step explanation:

The general rule of thumb is that the SMALLER a substance's atoms and the STRONGER the bonds, the harder the substance.

Two of the strongest forms of chemical bond are the ionic and the covalent bonds.